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Intravenous injection of heroin provides the greatest intensity and most rapid onset of euphoria (7 to 8 seconds), while intramuscular injection of heroin produces a relatively slow onset of euphoria (5 to 8 minutes). Users often experience nausea and vomiting the first time they take heroin, especially after injecting.
When heroin is sniffed or smoked, peak effects are usually felt within 10 to 15 minutes. Although smoking and sniffing heroin do not produce a "rush" as quickly or as intensely as intravenous injection.
According to the National Household Survey for 1994, 2.2 million Americans have tried heroin; 191,000 had used it in the previous 30 days.
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